Calculate:
For a primary outcome that is:
For trial type:
Note: This tool is for individual-level Randomized Control Trials (RCTs), not clustered RCTs.
Non-inferiority margin using absolute risk difference:
One-sided significance level or α-value (alpha):
Common/Recommended Value is 0.05
Two-sided significance level or α-value (alpha):
Common/Recommended Value is 0.05
Statistical power or 1-β value (1-beta):
Common/Recommended Value is 0.8
1. Based on available data and literature from other cohort studies or Randomized Control Trials (RCTs).